KMID : 0861220100120020047
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Journal of the Korean Society Clinical Neurophysiology 2010 Volume.12 No. 2 p.47 ~ p.54
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Correlation between Serum Lipid Level and Neurophysiological Findings in Patients with Carpal Tunnel Syndrome
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Yeo Seung-Hyeon
Kim Dong-Hoon Sohn Sung-Yun Hong Yoon-Hee Park Jae-Beum Joo In-Soo
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Abstract
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Background:Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy caused by compression of the median nerve beneath the transverse carpal ligament. CTS can be correctly diagnosed by the patients¡¯ description of symptoms and electrophysiological tests that measure nerve conduction through the wrist. Many previous studies reported various risk factors of CTS, such as obesity, diabetes mellitus, thyroid disease and trauma. Obesity is associated with both hyperlipidemia and CTS. This study focused on the relationship between severity of CTS and serum lipid level.
Methods:One hundred fourteen patients with CTS and 74 controls were divided into four groups according to the severity; normal, mild, moderate and severe. And then serum total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL-C) and high-density lipoprotein (HDL-C) were measured in each group.
Results:There was a positive correlation between TG and CTS severity (p<0.001). But TC, LDL-C and HDL-C were not correlated with CTS severity.
Conclusions:These results suggest that high serum TG may act as an aggravating factor of CTS.
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KEYWORD
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Carpal tunnel syndrome, Neurophysiology, Lipid, Triglyceride
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